The 100 most-cited articles in Heliyon, 2022

Liposomes are now considered the most commonly used nanocarriers for various potentially active hydrophobic and hydrophilic molecules due to their high biocompatibility, biodegradability, and low immunogenicity. Liposomes also proved to enhance drug solubility and controlled distribution, as well as their capacity for surface modifications for targeted, prolonged, and sustained release. Based on the composition, liposomes can be considered to have evolved from conventional, long-circulating, targeted, and immune-liposomes to stimuli-responsive and actively targeted liposomes. Many liposomal-based drug delivery systems are currently clinically approved to treat several diseases, such as cancer, fungal and viral infections; more liposomes have reached advanced phases in clinical trials. This review describes liposomes structure, composition, preparation methods, and clinical applications.

The simplicity, transparency, reliability, high efficiency and robust nature of PID controllers are some of the reasons for their high popularity and acceptance for control in process industries around the world today. Tuning of PID control parameters has been a field of active research and still is. The primary objectives of PID control parameters are to achieve minimal overshoot in steady state response and lesser settling time. With exception of two popular conventional tuning strategies (Ziegler Nichols closed loop oscillation and Cohen-Coon's process reaction curve) several other methods have been employed for tuning. This work accords a thorough review of state-of-the-art and classical strategies for PID controller parameters tuning using metaheuristic algorithms. Methods appraised are categorized into classical and metaheuristic optimization methods for PID parameters tuning purposes. Details of some metaheuristic algorithms, methods of application, equations and implementation flowcharts/algorithms are presented. Some open problems for future research are also presented. The…

The covid-19 pandemic revolutionises digital financial services, and hence digital financial inclusion is essential to ensure everyone can access digital financial services and thus promote sustainable economic growth. The development and activities promoting digital financial inclusion must align and help attain 2030 Sustainable Development Goals (SDGs). While the pandemic is anticipated to increase the usage of digital financial services, it has also created challenges for certain countries. Hence, a systematic literature review explores digital financial inclusion across countries. This research finds that developing countries, mainly Asian countries, embrace and improve digital financial inclusion to help reduce poverty. However, the results indicate that in developing countries, a persistent divide exists between gender, the wealthy and the poor, and urban and rural areas regarding access to and usage of digital financial services. At the end of the study, we propose a few recommendations, focusing on improving digital infrastructure, simplifying the complicated banking…

Issues related to depletion of conventional fuel resources and environmental concerns have become the driving force to explore an environment friendly, renewable, economical and sustainable alternate energy source. Huge quantities of agriculture biomass are being produced globally which can be transformed to biofuels by utilizing various procedures. However, issues such as environmental damages and competing uses of agriculture biomass need to be investigated factually considering the short as well as long-term acuity considering its effect on the soil and conversion to biofuels. This review provides an insight into the potential of various biomass as an energy source. Presently available conversion techniques to convert biomass to energy in various phases are discussed. The review also addresses the technical, socio-economic and environmental concerns and limitations with the appropriate control measures. Present study revealed that by the year 2020 most of the developed countries including the USA, Canada, China and Poland are switching to, renewable energy including agriculture…

The study of adsorbent behaviour in laboratory conditions helps to predict the adsorption process in a large industrial scale. In this study, orange and lemon peels-derived activated carbon (OLPAC) was successfully synthesized and activated using phosphoric acid. Characterization was performed on the OLPAC and the material was used for the removal of methyl orange (MO) and methylene (MB) dyes from wastewater. The results of the scanning electron microscope and N 2 adsorption/desorption examination affirmed that the prepared nanocomposite is permeable, which is an advantage for the efficient removal of contaminants. Optimal conditions for the batch removal process were investigated using a one-factor time approach in different conditions of adsorption (Dye concentration 50–200 mg L −1 , pH 2–10, adsorbent mass 0.010–0.8, and contact time 5–180 min. The adsorption isotherm equilibrium data were examined by Langmuir, Freundlich, and Temkin, isotherm model. As shown by the correlation coefficient (R 2 ), the data were best described by Langmuir isotherms with maximum adsorption…

Low-cost and renewable adsorbent activated carbon from lignocellulosic biomass is a focus of worldwide concern due to its readily available waste disposal problems in the environment. Physical and chemical processes are the main procedures forproduction of biomass-activated carbon (AC). Activating lignocellulosic biomass by chemical methods in terms of energy performance, lower timecarbonization, and temperature is mutual forthe production of activated carbon. Out of chemical activating agents (H 3 PO 4 , H 2 SO 4 , ZnCl 2 , FeCl 3 , NaOH, KOH, and K 2 CO 3 ), H 3 PO 4 is the most commonly used chemical activating agent during the synthesis of activated carbon from lignocellulosic biomass because of its ease of recovery, low environmental impact, and higher carbon yield. The surface area of most activated carbon from lignocellulosic biomass by H 3 PO 4 was in the variability of 456.1–2806 m 2 /g, yielding 26.1–85 % and an extreme adsorption capacity of 2.5–89.29 mg/g. And also, high acids to precursor ratio and activation temperature of AC were synthesized from lignocellulosic…

The development of materials for biomedical, aerospace, and automobile industries has been a significant area of research in recent years. Various metallic materials, including steels, cast iron, nickel-based alloys, and other metals with exceptional mechanical properties, have been reportedly utilized for fabrication in these industries. However, titanium and its alloys have proven to be outstanding due to their enhanced properties. The β-titanium alloys with reduced modulus compared with the human bone have found more usage in the biomedical industry. In contrast, the α and α+β titanium alloys are more utilized to fabricate parts in the automobile and aerospace industries due to their relatively lightweight. Amongst the numerous additive manufacturing (AM) techniques, selective laser and electron beam melting techniques are frequently used for the fabrication of metallic components due to the full densification and high dimensional accuracy they offer. This paper reviews and discusses the different types of AM techniques, attention is also drawn to the properties and challenges…

Global warming as a result of climate change has become a major concern for people all over the world. It has recently drawn the attention of the entire conscious community, with the fear that if not addressed properly, it will result in the extinction of numerous species around the world. At the same time, it will pose a threat to human health, food security, living environment and standard of living. Thereby, possible solutions are being explored accordingly; regulations have been imposed in places binding green production practices, limiting the emission of CO 2 and emphasis is given on renewable resources along with the search for alternatives to carbon-positive materials. Cannabis sativa L. (hemp) has received a lot of attention because of its multipurpose usability, short production cycle, low capital demand in cultivation, possibility of carbon-negative transformation and easy carbon sequestering material. This paper reviews hemp as a very promising renewable resource including its potential uses in paper, textiles, composites, biofuel, and food industry.

Climate change and socioeconomic developments are increasing the frequency and severity of floods. Flood management is widely recognized as an effective way to reduce the adverse consequences, and a more resilient and sustainable flood management approach has been the goal in recent studies. This study used a detailed bibliometric analysis of keywords, terms and timelines in the research field of the flood research. It provides new insight into the flood research trends, by examining the research frontiers from 2000 to 2021. We conclude that the trend of flood research has experienced a transition from flood control to flood resilience. The review shows that flood research has moved from traditional flood management, which provides mitigation strategies, to flood risk management, which provides an adaptation approach-adjusting mitigation measures, to flood resilience management, which provides a more resilient and sustainable plan to cope with flood disasters. We also present a detailed overview of the field of flood research, and review the definition of risk, risk analysis…

An approach to removing crystal violet (CV) dye from aqueous solutions was investigated by introducing a xanthate group on charred rice husk. The newly prepared charred rice husk (CRH) and xanthated rice husk (XRH) were characterized by XRD, SEM, FTIR, and elemental analysis. A batch technique was used to adsorb CV dye in aqueous suspensions. Different adsorbent quantities, concentrations, pH, and contact times were investigated to find the effect of these parameters. The optimum pH for both CRH and XRH was found to be 10. The adsorption capacity of CV dye onto CRH and XRH was found to be 62.85 mg/g and 90.02 mg/g at pH10, respectively. Langmuir isotherms could be reasonably explained by the experimental data. Within 60 min, equilibrium was achieved. Similarly, the kinetic data are best suited to the pseudo-second-order model. In comparison to XRH with CRH, XRH was found more efficient and can be used as a feasible alternative for removing CV dye from aqueous solutions.

The skin is a complex and multifunctional organ, in which the static versus dynamic balance is responsible for its constant adaptation to variations in the external environment that is continuously exposed. One of the most important functions of the skin is its ability to act as a protective barrier, against the entry of foreign substances and against the excessive loss of endogenous material. Human skin imposes physical, chemical and biological limitations on all types of permeating agents that can cross the epithelial barrier. For a molecule to be passively permeated through the skin, it must have properties, such as dimensions, molecular weight, pKa and hydrophilic-lipophilic gradient, appropriate to the anatomy and physiology of the skin. These requirements have limited the number of commercially available products for dermal and transdermal administration of drugs. To understand the mechanisms involved in the drug permeation process through the skin, the approach should be multidisciplinary in order to overcome biological and pharmacotechnical barriers. The study of the…

Environmental changes based on factors like urbanization, population, economic growth, increase in energy consumption, and agricultural intensification are never far from the top of any agenda. The topics of environmental degradation and climate change cannot be confined to a single country or region but need to be addressed on a global scale. If the focus is on the relationship between environmental degradation and economic growth, then one hypothesis that is comprehensively used as an empirically model is the widely known Environmental Kuznets Curve. A substantial amount of research has been published about the Environmental Kuznets Curve, and this present study provides a detailed and extensive literature review of more than 200 articles from 1998 to 2022 to explain and assess its evolution. This literature review provides in detail the Environmental Kuznets Curve relationship under analysis, the additional variables included, the type of analysis and methods performed, the relationships obtained, and if the turning point is calculated. Furthermore, this comprehensive literature…

Antibiotics do not differentiate between good and bad germs, disrupting normal microflora and causing vitamin deficiency in the human body. They also kill healthy bacteria in the gut and genital tract on a large scale, weakening the host's defense mechanism. Probiotics are a colony of bacteria that live in our intestines and are regarded as a metabolic 'organ' due to their beneficial effects on human health, including metabolism and immunological function. They are used in clinical settings to prevent and treat conditions such as diarrhoea, colon cancer, hypertension, diabetes, acute pancreatitis, Helicobacter pylori infection, ventilator-associated pneumonia, migraine and autism. Probiotics may modify immunological activity by increasing innate and adaptive immune responses, altering microbial habitat in the intestine, improving gut barrier function, competitive adherence to the mucosa and epithelium, and producing antimicrobial compounds. The aim of this study is to index that further in depth researches to be conducted on probiotics pivotal role in the prophylaxis and therapeutic…

Even though nanotechnology is extensively applied in agriculture, biochemistry, medicine and many other sectors, it is a developing field that conforms to new and more complex applications in food systems as compared to other technologies. It offers a viable strategy for integrating cutting-edge technology into a wide range of operations related to the production, development, fabrication, packaging, storage and distribution of food. The most fundamentally sophisticated technology in nano-based food science, nanoparticles deal with a wide range of nanostructured materials and nano methods, including nanofood, nanotubes, nanocomposites, nano packaging, nanocapsules, nanosensors, liposomes, nanoemulsions, polymeric nanoparticles and nanoencapsulation. This method is developed to increase food solubility and shelf life, availability of bioactive chemical, the protection of food constituents, nutritional supplementation, fortification and food or constituent delivery. Additionally, it serves as an antibacterial agent by generating reactive oxygen species (ROS) which cause bacterial DNA…

Globally, small and medium-sized enterprises (SMEs) compete and work on their sustainability in order to survive and thrive. SMEs rely only on their internal strength, and this strength lies mainly in their employees. Maintaining employees and their engagement increases productivity not only in terms of employee performance but also in terms of organizational performance. Based on social bond theory, the link between leaders and employees empowers the employees; in this context, the present research addresses how SMEs' potential effectiveness is derived from the employees when leadership plays its role efficiently and promotes voluntary work among employees. Using a sample of 405 employees from Pakistani SMEs, this paper assesses the effect on them of organizational citizenship behavior and transformational leadership, in terms of engaging them in voluntary work that ultimately improves performance; this helps SMEs flourish domestically and internationally. The present research also expands the literature by examining the mediating effect of organizational citizenship behavior and…

Background: Using a theoretical perspective to guide research design and implementation can result in a coherent preventative intervention model. Among theoretical frameworks, Bandura's Social Cognitive Theory (SCT) is particularly useful for studies focused on behavior change in health promotion research. Objective: This scoping review explored and summarized the current evidence on health promotion interventions that integrated constructs of Social Cognitive Theory and the outcome of those interventions in primary care settings. Method: ology: We conducted this scoping review using the PRISMA scoping review guidelines; we reviewed articles from five electronic databases and additional sources that were peer-reviewed journal articles reporting interventions applying SCT constructs and synthesized the outcomes following the interventions. Results: Among 849 retrieved from multiple sources, 39 articles met our eligibility criteria. Most studies (n = 19) were conducted in the United States. Twenty-six studies followed a randomized control trial design. Most studies (n = 26) recruited…

Individuals attempting to study remotely during the COVID-19 lockdown will find that blended learning is a helpful solution and results in a significant increase in learning engagement. The best benefits for teachers and students are obtained by maximizing the advantages of each teaching method and by combining the advantages of online and face-to-face instruction. The study aims to investigate the effectiveness of the flex model of blended learning in teaching the mathematics subtopic of coordinates in the plane through the improvement of students' academic achievement, self-study skills and learning attitudes. A quasi-experiment was conducted to compare the academic achievement, self-study skills and learning attitudes of 46 students in the control class who used traditional methods to those of 44 students in the experimental group who used the blended learning model. The pre-and post-test results, observations, and student opinion survey were used to compile data, which were then analyzed quantitatively (with SPSS) and qualitatively. The study confirmed that blended learning…

Background: Due to the range of conflicting criteria regarding minimum sample size needed for a scale/questionnaire validation study, the objective of this review is to analyze sample sizes used in published journal articles to contribute a pragmatic perspective to the discussion on sample sizes. Methods: A sample of 1999 articles published in a Scopus-indexed journal about the validation of a scale or questionnaire during 2021 were analyzed for this study. Abstracts from these articles were tabulated by two data entry professionals and any discrepancies were reviewed by the author. The sample size data was grouped by highest quartile of the journal publishing the article and further sub-categorized based on the inclusion of medical patients or students in each study's population. Results: From the total sample, 1750 articles provided sufficient information in their summary to determine the sample size used. Of these, the majority were published in quartile 1 (784) and quartile 2 (620) journals. Mean values by quartile ranged from 389 (quartile 3) to 2032 (quartile 1), but extreme…

Increased demand for water, energy, infrastructure, and other natural resources has resulted from an increase in anthropocentric activities recently, which has led to climate change, land erosion, pollution growth, and a decline in biodiversity. During the period 1972-2021, the aim of this study is how industrialization, urbanization, and renewable energy affect the environment of five industrialized economies-Brazil, Russia, India, China, and South Africa (BRICS)-implemented. Concerning slope heterogeneity, cross-sectional dependence (CSD), and a mixture of I (0) and I (1) variables, this paper used a fresh panel technique known as cross-sectionally augmented autoregressive distributive lag (CS-ARDL). When it comes to protecting water, land, and forest resources while also lowering carbon emissions, the estimate of energy, urbanization, electrification, and industrialization is favorably substantial. The findings show that rising industrialization, urbanization, income, and electrification can stimulate environmental degradation. On the other hand, renewable energy in…

L.) is a wild herbaceous perennial blooming plant that is commonly known as stinging nettle. It's a common, multi-purpose crop that's sometimes overlooked. Europe, Asia, North Africa, and North America are all home to stinging nettle. It is a plant that's edible and has nutritional and medicinal properties. Young leaves can be used to make curries, herb soups, and sour soups. The root of the stinging nettle is used to treat mictional difficulties associated with benign prostatic hyperplasia, while the leaves are used to treat arthritis, rheumatism, and allergic rhinitis. Its leaves are abundant in fiber, minerals, vitamins, and antioxidant compounds like polyphenols and carotenoids, as well as antioxidant compounds like polyphenols and carotenoids. Stinging nettle has antiproliferative, anti-inflammatory, antioxidant, analgesic, anti-infectious, hypotensive, and antiulcer characteristics, as well as the ability to prevent cardiovascular disease, in all parts of the plant (leaves, stems, roots, and seeds). Stinging nettle improves fish reproductive performance, making it a…

Antimony (Sb) chalcogenides such as antimony selenide (Sb 2 Se 3 ) and antimony sulfide (Sb 2 S 3 ) have distinct properties to be used as absorber semiconductors for harnessing solar energy including high absorption coefficient, tunable bandgap, low toxicity, phase stability. The potentiality of Sb 2 Se 3 and Sb 2 S 3 as absorber material in Al/FTO/Sb 2 Se 3 (or Sb 2 S 3 )/Au heterojunction solar cells (HJSCs) with 2D tungsten disulfide (WS 2 ) electron transport layer (ETL) layer has been investigated numerically using SCAPS-1D solar simulator. A systematic investigation of the impact of physical properties of each active material of Sb 2 Se 3 , Sb 2 S 3, and WS 2 on photovoltaic parameters including layer thickness, carrier doping concentration, bulk defect density, interface defect density, carrier generation, and recombination. This study emphasizes the exploration of causes of low performance of actual devices and demonstrates the individual variation in the open-circuit voltage (V OC ), short-circuit current density (J SC ), fill factor (FF), power conversion efficiency (PCE)…

This study reviews Islamic FinTech research development from 2017 to 2022. The study adopts a hybrid approach combining bibliometric and content analysis to reveal the current research trend of Islamic FinTech research. Using the Scopus database, we retrieve 85 documents and analyze them using RStudio and VOSviewer. The content analysis categorizes the research output in Islamic FinTech into four distinct streams. The study finds potential for cointegrating FinTech into Islamic finance to benefit the unbanked and small-medium-size businesses, the adoption of FinTech in Islamic finance will also help the government improve financial inclusion, conquer financial crises, such as COVID-19, and achieve SDGs for a sustainable nation. However, the lack of legal regulation and the lower financial literacy becomes the primary obstacle to the development of FinTech in Islamic finance.

The multidrug resistance phenomenon presents a major threat to the pharmaceutical industry. This resistance is a common occurrence in several diseases and is mediated by multidrug transporters that actively pump substances out of the cell and away from their target regions. The most well-known multidrug transporter is the P-glycoprotein transporter. The binding sites within P-glycoprotein can accommodate a variety of compounds with diverse structures. Hence, numerous drugs are P-glycoprotein substrates, with new ones being identified every day. For many years, the mechanisms of action of P-glycoprotein have been shrouded in mystery, and scientists have only recently been able to elucidate certain structural and functional aspects of this protein. Although P-glycoprotein is highly implicated in multidrug resistant diseases, this transporter also performs various physiological roles in the human body and is expressed in several tissues, including the brain, kidneys, liver, gastrointestinal tract, testis, and placenta. The expression levels of P-glycoprotein are regulated by different…

Lignocellulose is the most abundant biomass available on earth, including wood and agricultural wastes such as rice straw, corn cobs, and oil palm empty bunches. The biopolymer content in lignocellulose has a great potential as feedstock for producing industrial raw materials such as glucose, sorbitol, xylose, xylitol, and other pharmaceutical excipients. Currently, scientists and governments agree that the enzymatic delignification method is an environmentally friendly green method to be applied. This review attempts to explain the proper preparation of the enzymes laccase, lignin peroxidase, and manganese peroxidase, as well as the important factors influencing their activity. The recent applications of the enzymes for detoxification of hazardous substances, proper enzyme immobilization technique, and future prospect combination with DESs extraction of lignin are also discussed.

Currently, comparisons between biochar and activated carbon in terms of performance, environmental impacts as well as financial implications are limited. In this study, biochar sourced from date palm waste were analysed using gate-to-grave life cycle assessment approach and results were compared to activated carbon derived from woody biomass. Simapro 8.5 software was used to quantitatively simulate the environmental impacts of both adsorbents. Date palm waste biochar and activated carbon global warming potentials (GWPs) were found to be 1.53 and 8.96 kg CO 2eq /kg respectively. The cumulative energy demand (CED) for producing date palm waste biochar was found to be 20.3 MJ/kg, whereas, activated carbon resulted in 119.5 MJ/kg. Both adsorbents' performance in terms of adsorption capacity were compared, and it was found that biochar is comparable with activated carbon. The economic performance demonstrated that the average cost of production of date palm waste biochar and activated carbon were $1.06/kg and $1.34/kg, respectively. Sensitivity analysis showed that when the source of…

Continuous environmental degradation, volatility in the oil market, and unimpressive functioning of fossil-based (FB) fuels in compression ignition engines have expanded the tempo of the search for alternative fuels. Due to the astronomical rise in global population, improved agricultural, commercial, and manufacturing activities, enhanced farming and other food production and utilization ventures, agricultural waste generation, renewable fuel consumption, and emission of toxic gases. The need for cost-effective, readily available, and environmentally benign agricultural waste to biofuels has never been more crucial. Biofuels are renewable, biodegradable, low-cost, and eco-friendly fuels that are produced by microorganisms from waste lignocellulosic biomass. Conversion of agricultural wastes to biofuel does not exacerbate food security, contributes to waste management, prevents environmental degradation, and ensures energy security. This study reviews the conversion of agricultural wastes into biofuels with special emphasis on bioethanol, biohydrogen, biobutanol, biomethane,…

Recent advancements in virtual reality technology have attracted increasing attention from enterprises and scholars, and many new related products have been launched. Due to the current COVID-19 epidemic, the non-face-to-face teaching environment will seriously affect students' basketball learning. We therefore combined basketball learning with metaverse technology, discussed basketball teaching in a virtual reality environment, and examined the influencing factors of college students' intentions to use metaverse technology. In the light of UTAUT2, a new research model was proposed, and quantitative research was carried out. The results of a survey of 1074 valid samples revealed that habits and attitudes are crucial factors in the success of basketball learning using a metaverse. The findings also indicate that grade and gender are moderator variables.

The discovery of plastics as useful materials for human existence, providing comfort and ease has now turned into a menace in the society and a pain in the neck as plastics have also become co-habitat of the human ecosystem. Plastics were made by men, but plastics now live way longer than the men who gave them the privilege of existence. Since these colonies of materials cannot be eradicated, it is very pertinent to discover possible ways of useful diversion through recycling by converting plastic bottle waste into useful raw materials for other sectors of the economy. This paper has stirred the pool of relevant literature to extract some of the innovative efforts that have been deployed into redirecting the potential of plastic waste into useful applications like engineering and building construction, horticulture in agriculture, and the most advanced application is the 3D printing using plastics as filaments. Following the trend of technology, 3D printing is a grey area of plastic recycling, it is quite expensive however, it worth exploring.

This paper reviews the pertinent literature from 1970 to 2020 and presents a bibliometric analysis of research trends in the application of solid-state fermentation in the bioprocessing of agro-industrial wastes. A total 5630 publications of studies on solid-state fermentation that comprised of 5208 articles (92.50%), 340 book chapters (6.04%), 39 preprints (0.69%), 32 proceedings (0.56%), 8 edited books (0.14%) and 3 monographs (0.05%) were retrieved from Dimensions database. A review of the literature indicated that (i) fermentation of solid substrates is variously defined in the literature over the past 50 years, where "solid-state fermentation" is the most dominant research term used, and (ii) key products derived from the valorization of agro-industrial wastes through solid-state fermentation include, among others, enzymes, antioxidants, animal feed, biofuel, organic acids, biosurfactants, etc. Bibliometric analyses with VOSviewer revealed an astronomic increase in publications between 2000 and 2020, and further elucidated the most frequently explored core research topics, the…

Raw date seeds, as prospective natural, broadly obtainable and low-price agricultural waste for adsorbing cationic dyes from aqueous solutions, have been studied. In this work, Iraqi date seeds were prepared and characterised using X-ray diffraction (XRD), scanning electron microscopy (SEM), Fourier transform infrared (FTIR) spectroscopy and Brunauer–Emmett–Teller (BET) surface area analysis before being used as an efficient bio-adsorbent for methyl violet (MV) dye removal. Adsorption tests were conducted with three investigated parameters, namely, time of contact, first adsorbate concentration and adsorbent dose. Compared with the pseudo first-order model (coefficient of determination=0.9001), the pseudo second-order model was determined to be the best-fitting model with a coefficient of determination (R 2 ) of 0.9917. The equilibrium isotherms for MV were obtained, and their ultimate capacity of adsorption was (59.5 mg g 1 ). Two isotherm models, Langmuir and Freundlich, were studied to fit the equilibrium data. Compared with the Freundlich isotherm model (R 2 = 0.8154), the…

Human Action Recognition (HAR) is a challenging task used in sports such as volleyball, basketball, soccer, and tennis to detect players and recognize their actions and teams' activities during training, matches, warm-ups, or competitions. HAR aims to detect the person performing the action on an unknown video sequence, determine the action's duration, and identify the action type. The main idea of HAR in sports is to monitor a player's performance, that is, to detect the player, track their movements, recognize the performed action, compare various actions, compare different kinds and skills of acting performances, or make automatic statistical analysis. As an action that can occur in the sports field refers to a set of physical movements performed by a player in order to complete a task using their body or interacting with objects or other persons, actions can be of different complexity. Because of that, a novel systematization of actions based on complexity and level of performance and interactions is proposed. The overview of HAR research focuses on various methods performed on…

Some of the health issues that are becoming more prevalent each year include bone disease and fractures. Because the natural healing process of bones takes a long time, a bone grafting procedure is required so that the patient's condition can improve rapidly. Because bone grafting procedures such as autographs, allographs, and xenografts have limits, bone replacement is constructed by employing biomaterials in the form of a bone scaffold via additive manufacturing. As a result, fused deposition modeling (FDM) is a proposed technology for the manufacturing process because it is straightforward, capable of producing complex parts and adjustable shapes, and has minimal operational expenses. However, implementing this technique is challenging because of the scarcity of biocompatible and bioactive materials that are suited. This technology has a number of limitations, including a limited variety of biocompatible and bioactive materials, the most appropriate microarchitecture of bone scaffold, and the establishment of printing parameters that can produce bone scaffold with the strongest…

Objective: To investigate the burden of untreated dental caries in 204 countries and territories over 30 years. Methods: Data of untreated dental caries from 1990 to 2019, including the incidence, prevalence, and years lived with disability, were extracted from the Global Burden of Disease 2019 database. Estimated annual percentage changes were calculated to assess the changes in the age-standardized incidence, prevalence, and years lived with disability rates. Results: Globally, in 2019, there were 3.09 billion (95% uncertainty interval [UI]: 2.76-3.39 billion) new cases of untreated dental caries in permanent teeth (48.00% increase), 2.03 billion (1.77-2.33) prevalent cases (46.07% increase), and 2.00 million (0.93-3.88) YLDs (45.64% increase), all since 1990. From 1990 to 2019, the age-standardized incidence rate (ASIR) of untreated dental caries in permanent teeth showed an upward trend (estimated annual percentage changes [EAPC] = 0.01), but age-standardized prevalence rate (ASPR) (EAPC = -0.13) and age-standardized YLD rate (ASYR) (EAPC = -0.13) decreased. There were 1.15…

In this study, 11 hydroxybenzoic acids, 6 hydroxycinnamic acids, 6 flavonoids, and 2 synthetic phenolic antioxidants were evaluated according to their scavenging capacity and structure relationships. The IC50 was calculated for all compounds and the effects of the concentration of antioxidant and the length of the reaction on antioxidant capacity were taken into consideration. Based on the data of tested phenolics some structure-activity relationships were suggested and discussed in detail. Poor correspondence of the results between ABTS+• and DPPH• assays was attained, indicating that the antioxidant properties of each compound differ with regards to the applied method. Nevertheless, it can be argued that the number of electron-donating substituents (-OH and -OCH3) and their configuration has a significant impact on the antioxidant capacity. Undoubtedly, concerns about the reliability of these assays demand further in-depth investigations to give detailed insight into the structure and antioxidant activity relationships.

Cisplatin spearheads the anticancer chemotherapeutics in present-day use although acute toxicity is its primary impediment factor. Among a plethora of experimental medications, a drug as effective or surpassing the benefits of cisplatin has not been discovered yet. Although Oxaliplatin is considered more superior to cisplatin, the former has been better for colorectal cancer while cisplatin is widely used for treating gynaecological cancers. Carcinoma imposes a heavy toll on mortality rates worldwide despite the novel treatment strategies and detection methods that have been introduced; nanomedicine combined with precision medicine, immunotherapy, volume-regulated anion channels, and fluorodeoxyglucose-positron emission tomography. Millions of deaths occur annually from metastatic cancers which escape early detection and the concomitant diseases caused by highly toxic chemotherapy that causes organ damage. It continues due to insufficient knowledge of the debilitative mechanisms induced by cancer biology. To overcome chemoresistance and to attenuate the adverse effects of cisplatin…

Agriculture is a backbone of global economy and most of the population relies on this sector for their livelihood. Chitosan as a biodegradable material thus can be explored for in various fields in its nano form to replace non-biodegradable and toxic compounds. The chitosan has appealing properties like biocompatibility, non-toxicity, biodegradability, and low allergenic, making it useful in several applications including in agriculture sector. Because of their unique properties, chitosan nanoparticles (ChNPs) are extensively applied as a bioagent in various biological and biomedical processes, including wastewater treatment, plant growth promoter, fungicidal agent, wound healing, and scaffold for tissue engineering. Furthermore, the biocompatibility of chitosan nanoparticles (ChNPs) is reported to have other biological properties such as anti-cancerous, antifungal, antioxidant activities, even induces an immune response in the plant, and helps manage biotic and abiotic stresses. Chitosan can also find its application in wastewater treatment, hydrating agents in cosmetics, the food…

The population aging and an increased life expectancy are widely recognized social changes. Technologies are believed to improve the elderly's daily lives and maintain their health efficiently. Despite the advantage of adopting technologies, the elderly are slower to adopt new technologies compared to younger adults. This paper presents a Systematic Literature Review (SLR) to identify the different antecedents prevailing in the literature on elderly technology adoption. The SLR classifies and analyzes 26 relevant articles on elderly's technology adoption. Our findings revealed that quantitative approach and cross-sectional studies predominate in this field, building fundamentally upon the technology-driven theories. We identify seven categories of antecedents influencing elderly's use of technology, namely, technology, psychological, social, personal, cost, behavior, and environment antecedents. A conceptual framework for elderly's technology adoption and recommendations were presented. Particular attention is given to the need for in depth study for the antecedents, development of…

Biogas is a promising bioenergy alternative to be recovered from waste/wastewater in the context of environmental sustainability and circular economy. However, raw biogas contains various secondary impurities such as carbon dioxide, hydrogen sulphide, siloxanes, nitrogen oxides (NOx), ammonia, and halogens. Depending on the emission rate of these biogas impurities, the importance of biogas is being hampered for its environmental, health and the detrimental effects possess by the impurities towards the downstream of the biogas users. Biogas impurities can cause different public health concerns (like pulmonary paralysis, asthma, respiratory diseases and deaths) and environmental impacts (such as global warming, climate change and their indirect impacts like drought, flooding, malnutrition and other disasters). The absence/inconsistent emission standards among countries, agencies, and other stakeholders is the other challenge that they possess during monitoring and controlling of these impurities. Different commercially available and emerging technologies are available for separating…

The textile industry uses large amounts of dyes like reactive, azo, anthraquinone, and triphenylmethane to colour textiles. Dyes that are not used up during the colouration process usually end up in water bodies as waste leading to the pollution of the water bodies. This makes the industry to be one of the major contributors to water pollution in the world. Bacterial agents isolated from various sources like dye contaminated soil and textile wastewater have shown to have the ability to effectively decolourise and degrade these dye pollutants leading to improved water quality. This review discusses bacterial isolates that have been used successfully to degrade and decolourise textile dyes, their mode of dye removal as well as the factors that affect their dye degradation ability. It further looks at the latest wastewater treatment technologies that incorporate bacterial microorganisms to treat dye wastewater.

The occurrence of emerging contaminants (ECs) such as pharmaceuticals, personal care products (PPCPs) and pesticides in the aquatic environment has raised serious concerns about their adverse effects on aquatic species and humans. Because of their toxicity and bioactive nature, PPCPs and pesticides have more potential to impair water systems than any other contaminants, causing several adverse effects, including antibiotic resistance, reproductive impairment, biomagnification, bioaccumulation, etc. Over 35 publications from Africa have reported on the occurrence and fate of PPCPs and pesticides in African water systems with little or no data on remediation and control. As a result, adequate intervention strategies are needed for regulating the persistence of PPCPs and pesticides in African water systems.

Direct-Ink-Writing (or robocasting) is a subset of extrusion-based additive manufacturing techniques that has grown significantly in recent years to design simple to complex ceramic structures. Robocasting, relies on the use of high-concentration powder pastes, also known as inks. A successful optimization of ink rheology and formulation constitutes the major key factor to ensure printability for the fabrication of self-supporting ceramic structures with a very precise dimensional resolution. However, to date achieving a real balance between a comprehensive optimization of ink rheology and the determination of a relevant protocol to predict the printing parameters for a given ink is still relatively scarce and has been not yet standardized in the literature. The current review reports, in its first part, a detailed survey of recent studies on how ink constituents and composition affect the direct-ink-writing of ceramic parts, taking into account innovative ceramic-based-inks formulations and processing techniques. Precisely, the review elaborates the major factors influencing on ink…

Salinity is one of the most significant environmental factors limiting microalgal biomass productivity. In the present study, the model microalga Chlamydomonas reinhardtii ( C. reinhardtii ) was exposed to 200 mM NaCl for eight days to explore the physiological, biochemical and metabolomic changes. C. reinhradtii exhibited a significant decrease in growth rate, and Chl a and Chl b levels. 200 mM NaCl induced ROS generation in C. reinhardtii with increase in H 2 O 2 content. This caused lipid peroxidation with increase in MDA levels. C. reinhardtii also exhibited an increase in carbohydrate and lipid accumulation under 200 mM NaCl conditions as storage molecules in cells to maintain microalgal survival. In addition, NaCl stress increased the content of carotenoids, polyphenols and osmoprotectant molecules such as proline. SOD and APX activities decreased, while ROS-scavenger enzymes (POD and CAT) decreased. Metabolomic response showed an accumulation of the major molecules implicated in membrane remodelling and stress resistance such oleic acid (40.29%), linolenic acid (19.29%),…

Phenolic compounds are plant secondary metabolites that play a vital role in plant resistance. They are mainly synthetized from the amino acid L-phenylalanine, which is converted to trans-cinnamic acid in a series of biochemical reactions. These compounds take part in the regulation of seed germination and cooperate in regulating the growth of plants, also taking part in defense responses during infection, UV exposure, injuries, and heavy metal stress. The aim of this review is to discuss the role of phenolic compounds in the interactions of plants with various stress factors, both biotic and abiotic with special attention to their antioxidant properties. Therefore, understanding the biochemical potential of the phenylpropanoid derivatives would be beneficial in sustaining the metabolic processes used by plants to thrive and endure under adverse conditions.

Agriculture crops encounter several biotic and abiotic stresses, including pests, diseases, nutritional deficits, and climate change, which necessitate the development of new agricultural technologies. By developing nano-based fertilizers, insecticides and herbicides, and early disease diagnostics, nanotechnology may help to increase agricultural crop quality and production. The application of silica nanoparticles (SiNPs) may be the solution for increasing the yield to combat the agriculture crisis in the near future. SiNPs have unique physiological properties, such as large surface area, aggregation, reactivity, penetrating ability, size, and structure, which enable them to penetrate plants and regulate their metabolic processes. Pesticide delivery, enhanced nutrition supply, disease management, and higher photosynthetic efficiency and germination rate are all attributed to SiNPs deposition on plant tissue surfaces. SiNPs have been demonstrated to be non-toxic in nature, making them suitable for usage in agriculture. In this regard, the current work provides the most important and…

Increasing untreated environmental outputs from industry and the rising human population have increased the burden of wastewater and other waste streams on the environment. The most prevalent wastewater treatment methods include the activated sludge process, which requires aeration and is, therefore, energy and cost-intensive. The current trend towards a circular economy facilitates the recovery of waste materials as a resource. Along with the amount, the complexity of wastewater is increasing day by day. Therefore, wastewater treatment processes must be transformed into cost-effective and sustainable methods. Microbial fuel cells (MFCs) use electroactive microbes to extract chemical energy from waste organic molecules to generate electricity via waste treatment. This review focuses use of MFCs as an energy converter using wastewater from various sources. The different substrate sources that are evaluated include industrial, agricultural, domestic, and pharmaceutical types. The article also highlights the effect of operational parameters such as organic load, pH, current, and…

Hydroxyapatite has recently played a crucial role in the sustainable development of biomedical applications. Publications related to hydroxyapatite as filler for biopolymers have exhibited an increasing trend due to the expanding research output. Based on the latest publications, the authors reviewed the research trends regarding hydroxyapatite use in biomedical applications. Analysis of the Scopus database using the keywords 'hydroxyapatite" and "biomedical applications" determined that 1,714 papers were produced between 2012 and 2021. The number of publications related to these keywords more than doubled between 2012 (99) and 2021 (247). The hydrothermal method, solid-state reactions, the sol-gel process, emulsion, micro-emulsion, and mostly chemical precipitation were used to produce synthetic hydroxyapatite. Meanwhile, calcination, alkaline hydrolysis, precipitation, hydrothermal, and a combination of these techniques were used in producing natural hydroxyapatite. Studies in the current literature reveal that shell-based animal sources have been frequently used as hydroxyapatite…

The development of science, technology, engineering, and mathematics (STEM) requires more qualified professionals in these fields. However, gender segregation in higher education in this sector is creating a gender gap that means that for some disciplines female representation does not even reach 30% of the total. In order to propose measures to address the phenomenon, it is necessary to understand the possible causes of this issue. A systematic literature review and mapping were carried out for the study, following the PRISMA guidelines and flowchart. The research questions to be answered were (RQ1) What studies exist on the gender gap in relation to the choice of higher education in the STEM field; and (RQ2) How do gender roles and stereotypes influence decision-making related to higher education? The review of peer-reviewed scientific articles, conferences texts, books and book chapters on the European education area was applied. A total of 4571 initial results were obtained and, after the process marked by the PRISMA flowchart, the final results were reduced to 26. The results…

Open Educational Resources (OER) are teaching, and research resources provided under the Creative Commons (CC) licenses and can be freely used, shared, and modified. However, OER adoption is not widespread, and various barriers remain in the way of its growing emphasis. This article is aimed to investigate OER adoption in higher institutions by using Rogers' Diffusion of Innovation (DOI) theory. 422 responses to an online survey from faculty are gathered and analyzed, where adaptive attributes of DOI are adopted. The results of the descriptive method confirmed that relative advantage has a positive impact on faculty OER adoption. Indeed, positive impacts of observability and complexity are also shown. Ultimately, the findings from the structural model used, indicated that there is a positive correlation between trialability and respectively complexity and compatibility. Whereas relative advantage of OER impacts positively complexity and negatively compatibility. This study showed that it is not enough that faculty agree on OER benefits for teaching and research, the OER adoption…

As the world's fourth most populous country, the population growth rate in Indonesia is expected to stay high. Owing to a combination of high-speed urbanization and increasing population density, economic growth is predicted to increase the demand for energy consumption. Thus, it is crucial to understand the relationship between population density and energy consumption in any country. This study evaluates the impact of population density on total energy consumption and the disaggregated electricity and fuel consumption at the provincial level in Indonesia. It uses the extended Stochastic Impacts by Regression on Population, Affluence, and Technology (STIRPAT) model. It also employed a balanced panel data of 33 provinces from 2010 to 2018. The results indicated that population density positively impacts energy consumption for total, electricity, and fuel consumption. This study suggests that incorporating population growth into national energy plans is crucial. Additionally, reducing energy inequality and uneven spatial distribution of the population is also needed.

It has been a challenge to support the expansion of urban agriculture (UA) in cities due to its poor economic profitability. However, it is also hard to deny the increasing benefits of UA in improving the socio-environmental dimension of cities. Hence, in this review, different aspects of UA were examined to highlight its value beyond profitability such as social, health and well-being, disaster risk reduction, and environmental perspectives. A case study and relevant policies were analyzed to determine how policy makers can bridge the gap between current and future UA practices and sustainable development. Bridging these policy gaps can help the UA sector to sustainably grow and become successfully integrated in cities. Moreover, advancements in UA technologies and plant biotechnology were presented as potential solutions in increasing the future profitability of commercial UA. Consequently, as new UA-related technologies evolve, the multidisciplinary nature of UA and its changing identity from agriculture to digital technology, similarly require adaptive policies. These policies…

The year 2021 is one of the most significant years for live streaming commerce, since numerous sectors and businesses have begun to sell their items in the form of live broadcast influence. Especially in China, Taobao live streaming often promotes an event by inviting internet celebrities to cooperate with brands to broadcast the products. For many brands, that is a very successful technique for increasing conversion rates. Researchers have lately grown interested in investigating the factors influencing the purchase decisions of Chinese consumers in the context of Taobao live streaming commerce with online celebrities. The present study is the first to theoretically combine three primarily literature-based disciplines, including source credibility, match-up hypothesis, and parasocial relationship theory, into a unified framework to bridge the research gaps. In this study, the quantitative method was employed through the use of partial least square structural equation modeling (PLS-SEM). The SmartPLS 3.0 software was applied to examine the proposed model. The data were obtained from…

An accurate carbon emissions measurement is critical for developing an appropriate climate strategy to address ecological issues. A meaningful climate policy reaction can be offered based on trade adjusted statistics of carbon emissions. This research utilizes second-generation panel co-integration techniques to investigate the influence of globalization and renewable energy utilization on consumption-based carbon emissions (CCO 2 ) as well as the role of nonrenewable energy use and economic growth in the MINT-(Mexico, Indonesia, Nigeria and Turkey) countries from 1990 to 2018. The outcomes of the cross-sectional dependency and heterogeneity tests revealed slope heterogeneity and cross-sectional units across nations. Furthermore, the outcomes of the cointegration test provided evidence of a long-run association between consumption-based CO 2 emissions (CCCO 2 ) and the regressors. Moreover, the outcomes of both common correlated effect mean group ( CCEMG ) and augmented mean group (AMG) unveiled that economic growth and nonrenewable energy utilization contribute to the degradation…

Electrocoagulation (EC) is a process used by supply of electric current with sacrificial electrodes for the removal of pollutant from wastewater. The study was experimentally investigated taking into account various factors such as pH (3-7.5), current (0.03-0.09 A), distance between the electrodes (1-2 cm), electrolytic concentration (1-3 g/L), and electrolysis time (20-60 min) which is impact on the % removal efficiency of color, chemical oxygen demand (COD), turbidity and determination of energy consumption used for aluminum (Al) electrode used. The surface response design process based on the central composite design (CCD) has been used to optimize different operational parameters for treatment of hospital wastewater using EC process. The % color, COD and turbidity removal, and energy consumption under different conditions were predicted with the aid of a quadratic model, as were the significance and their interaction with independent variables assessed by analysis of variance (ANOVA). The optimal conditions were obtained through mathematical and statistical methods to reach…

Investigators were continuously creating novel nanotechnologies to address unmet requirements throughout the administration of therapeutic medicines & imaging agents for cancer treatment & diagnostics, appropriately. LNPs(Lipid nanoparticles) are legitimate particulates (approx. 100 nm in size) gathered from various lipid as well as other biochemical compounds which overall functionality to resolve biological barriers (biobarriers), allowing LNPs to selectively collect somewhere outside of disease-target cells again for responsive therapeutics. Most pharmaceutically important compounds were insoluble throughout water solutions, were chemical & physiologically unstable, or have toxicities. Among the most potential drug carrier for bioactive organic compounds is LBNPs (Lipid based nanoparticles) technologies. Its present use in chemotherapy have transformed treatment for cancer by increasing the antitumor effect of a number of chemotherapeutics. Because they may be created using naturally occurring sources, LBNPs have great temporal and thermal stability, maximum load potential,…

This study aims to analyze the significant socioeconomic and environmental impacts of construction waste and to indicate management strategies. An extensive review of the literature and interviews with construction experts were used to identify waste impact factors. Then a questionnaire survey was conducted based on a five-point Likert scale and the data were analyzed by descriptive statistics. The result showed that construction waste becomes a challenge for almost 95.71% of ongoing construction projects. However, only 57.14% of the construction companies have recorded and measured the volume of material waste. From purchased materials, 6-10% is recorded as waste that lead to project cost overrun. In addition, there is no professional assigned to handle waste issues in 75.71% of construction companies. The study also indicates that project cost overrun, pollution of the environment, reduction in profit and failure of construction firms, excessive consumption of raw materials, and public health and safety risks are ranked as the five major impacts of construction waste,…

Due to their natural availability, biocompatibility, biodegradability, nontoxicity, flexibility, as well as improved structural and functional characteristics, pectin and pectin-based nanocomposites have become an interesting area of numerous researchers. Pectin is a polysaccharide that comes from plants and is used in a variety of products. The significance of pectin polysaccharide and its modified nanocomposites in a number of applications has been shown in numerous reviews. On their uses in pharmaceutical and medication delivery, there are, however, few review publications. The majority of papers on pectin polysaccharide do not structure their explanations of drug distribution and medicinal application. The biological application of pectin nanocomposite is also explained in this review, along with a recent publication. As a result, the goal of this review was in-depth analysis to summarize biological application of pectin and its modified nanocomposites. Due to their exceptional physicochemical and biological characteristics, pectin and its nanocomposites are remarkable materials…

Researchers are developing digital solutions for agriculture. Humanity has perfected agriculture throughout history because this activity is fundamental to our existence. The agricultural sector is currently incorporating new technologies from other areas. This phenomenon is agriculture 4.0. However, a challenge to research is the integration of technologies from different knowledge fields, and this has caused theoretical and practical difficulties. Thus, our purpose with this study has been to understand the core agriculture 4.0 research themes. We have used a bibliometric analysis, and guided the data collection by the PRISMA protocol. VosViewer and Bibliometrix software generated the results. We found two main research fronts, one focussed on agriculture 4.0 development, and another on the impacts of agriculture 4.0, which may be positive or negative. We found 21 main keywords or topics researched in agriculture 4.0 related to these research fronts. These themes are within five different axes. We managed to establish a good understanding of the topics around agriculture 4.0.…

Military applications and the aeronautic industry are increasingly interested in aluminum lithium alloys (Al-Li) because of the properties required due to the presence of Lithium, which provides a very considerable gain concerning the mechanical properties compared to conventional aluminum alloys. The research and development departments are interested in improving these alloys especially in additive manufacturing process, which leads today to focus on the 3rd generation of Al-Li in terms of part quality - low density compared to the 1st and the 2nd generation. The objectives of this paper is to present a review of Al-Li alloys applications, its carachetrization, the precipitations and their impact on mechanical properties and grain refinement. The various manufacturing processes, methods and tests used are then deeply investigated and presented. The last investigations that have been gotten by scientists over the previous few years on Al-Li for different processes are also reviewed in this research.

The coronavirus disease 2019 (COVID-19) pandemic has severely affected Thailand's economy, which relies heavily on tourism. In this study, we labeled the sentiment and intention classes of English-language tweets related to tourism in Bangkok, Chiang Mai, and Phuket. Then, the accuracy of three machine learning algorithms (decision tree, random forest, and support vector machine) in predicting the sentiments and intentions of the tweets was investigated. The support vector machine algorithm provided the best results for sentiment analysis, with a maximum accuracy of 77.4%. In the intention analysis, the random forest algorithm achieved an accuracy of 95.4%. In a subsequent preliminary qualitative content analysis, the top 10 words found in each sentiment and intention class were gathered to provide insights and suggestions to help increase tourism in Thailand. The results of this study suggest that to help restore tourism in Thailand, tourist destinations, natural attractions, restaurants, and nightlife should be promoted. In addition, the two main concerns of tourists to Thailand…

Developing bio-based self-healing concrete aims to minimize durability problems related to cracking. In this study, MICP was used as a smart and eco-friendly approach to produce bio-based durable materials. Bacillus pasteurii (BP) and Bacillus sphaericus (BS) were added into mortar mixtures with 0.25% and 0.5% cement weight. All treated samples exhibited a significant decline in water uptake, capillary permeability, and volume of permeable voids, as compared to control with no bacteria. All treated samples showed significant increase in compressive strength by 28–50%, after 28 days of curing. At the age of 120 days, the flexural strength of all treated samples was significantly increased by 19.29–65.94%. SEM imaging and EDAX confirmed that treated samples were denser with less voids due to MICP. DTA verified that the calcite amount and the crystallinity degree were improved in treated samples. Load deflection of bacterial Reinforced-Laminates had less deformation than control. Reloaded bacterial Reinforced-Laminates exhibited excellent restoration of physico-mechanical properties…

The purpose of this study is to provide a comprehensive review of e-learning in higher education institutions (HEIs) during the COVID-19 pandemic. This study presents current research issues and future progress in HEIs e-learning in the wake of the COVID-19 pandemic from 2019 to 2020 through the Web of Science (WOS) database. The analysis comprises citation analysis, co-citation analysis, and co-occurrence of keyword analysis. This bibliometric review provides essential insight for researchers to identify the most influential publications and determine the fundamental structure. Furthermore, this review facilitates future studies on the influential research trends and emerging topics. Findings present several streams of discussion based on the clusters identified from the three analyses. Subsequently, the theoretical and methodological implications on the emergence of new sub-fields and interesting future works in connection with e-learning in HEIs are presented. The outcome would aid scholars and practitioners in advancing the technology and aid towards e-learning in HEIs to ensure…

The past decade has seen a significant shift from teacher-centered pedagogy to a learner-centered approach in chemistry education research. Game-based learning has emerged as one of the most beneficial instructional approaches because it emphasizes "hands-on" and "minds-on" activities in chemistry classrooms. However, there has been a scarcity of review studies in chemistry education research that have attempted to document different educational games implemented and how such games have contributed to enhancing students' motivation and understanding of chemistry concepts. A total of 57 articles were reviewed to identify educational games implemented in chemistry classrooms from 2010 to 2021 to address this gap. All the reviewed articles were downloaded from the Google Scholar search engine and have all been indexed by Scopus. A systematic analysis was adopted to identify the purposes, educational game designs and implementation, and the chemistry content areas of focus for all the reviewed studies. Results show that educational games enhance students' conceptual understanding of…

Biotechnologically useful yeast strains have been receiving important attention worldwide for the demand of a wide range of industries. Rhodotorula mucilaginosa is recognized as a biotechnologically important yeast that has gained great interest as a promising platform strain, owing to the diverse substrate appetites, robust stress resistance, and other gratifying features. Due to its attractive properties, R. mucilaginosa has been regarded as an excellent candidate for the biorefinery of carotenoids, lipids, enzymes, and other functional bioproducts by utilizing low-cost agricultural waste materials as substrates. These compounds have aroused great interest as the potential alternative sources of health-promoting food products, substrates for so-called third-generation biodiesel, and dyes or functional ingredients for cosmetics. Furthermore, the use of R. mucilaginosa has rapidly increased as a result of advancements in fermentation for enhanced production of these valuable bioactive compounds. This review focuses on R. mucilaginosa in these advancements and summarizes its…

The world has faced many disasters in recent years, but flood impacts have gained immense importance and attention due to their adverse effects. More than half of global flood destruction and damages occur in the Asia region, which causes losses of life, damage infrastructure, and creates panic conditions among the communities. To provide a better understanding of flood hazard management, flood vulnerability assessment is the primary objective. In this case, vulnerability is the central construct in flood analysis and assessment. Many researchers have defined different approaches and methods to understand vulnerability assessment and how geographic information systems assess the flood vulnerability and their associated risk. Geographic information systems track and predict the disaster trend and mitigate the risk and damages. This study systematically reviews the methodologies used to measure floods and their vulnerabilities by integrating geographic information system. Articles on flood vulnerability from 2010 to 2020 were selected and reviewed. Through the systematic review…

Adoption of climate smart agricultural (CSA) practices has been widely recognized as a promising and successful alternative to minimize the adverse impacts of climate change. However, their adoption among smallholder farmers remains low in developing countries, including Ethiopia. This study examines factors that influence adoption and the level of adoption of multiple CSA practices, including improved agronomy, soil and water conservation, drought tolerant high yielding crop variety, small-scale irrigation, integrated disease, pest, and weed management, and integrated soil fertility management, using survey data from 404 farm households in Bale-Eco Region (BER), Ethiopia. The study applied a multivariate probit model for analyzing the simultaneous adoptions of multiple CSA practices, and ordered probit model for examining the factors influencing the level of adoption. The CSA practices are found to be complementary. Moreover, farmers' adoption of multiple CSA practices, as well as their intensity of adoption, is significantly influenced by the age of the household head, education,…

Terminalia chebula Retz, commonly known as ‘Haritaki/Myrobalan,' has been utilised as a traditional medicine for a long time. It has been extensively exercised in various indigenous medicine practices like Unani, Tibb, Ayurveda, and Siddha to remedy human ailments such as bleeding, carminative, dysentery, liver tonic, digestive, antidiarrheal, analgesic, anthelmintic, antibacterial and helpful in skin disorders. Studies on the pharmacological effects of T. chebula and its phytoconstituents documented between January, 1996 and December, 2021 were explored using various electronic databases. During the time mentioned above, several laboratory approaches revealed the biological properties of T. chebula , including antioxidative, antiproliferative, anti-microbial, proapoptotic, anti-diabetic, anti-ageing, hepatoprotective, anti-inflammatory, and antiepileptic. It is also beneficial in glucose and lipid metabolism and prevents atherogenesis and endothelial dysfunction. Different parts of T. chebula such as fruits, seeds, galls, barks extracted with various solvent systems (aqueous,…

Cancer is one of the leading causes of death in the world. Chemotherapy is presented as an option for treatment of this disease, however, low specificity, high resistance rates, toxicity and hypersensitivity reactions, make it necessary to search for therapeutic alternatives that increase the selectivity of treatment, reduce the side effects and enhance its antitumor potential. Natural products are accessible, inexpensive and less toxic sources; in addition, they have multiple mechanisms of action that can potentiate the outcome of chemotherapeutics. In this review, we present evidence on the beneficial effect of the interaction of dietary phytochemicals with chemotherapeutical agents for cancer treatment. This effect is generated by different mechanisms of action such as, increased tumoricidal effect via sensitization of cancer cells, reversing chemoresistance through inhibition of several targets involved in the development of drug resistance and, decreasing chemotherapy-induced toxicity in non-tumoral cells by the promotion of repair mechanisms. Studies discussed in this review…

Fast fashion uses an excessive amount of synthetic dyes and chemical reagents in textile production, while a large quantity of fast fashion apparel and clothes go to the landfill, posting environmental safety concerns. Natural dyes not only produce delicate and subdued shades but also have the potential of novel features to achieve active textile substrate with performance properties such as deodorizing, antioxidant, antimicrobial, antifeedant, UV protection, etc. Developing colored textile products with natural colorants in today's market may enhance consumer interest to an even greater extent. Therefore, finding alternative natural degradable dyes has become one of the leading trends in this field. So far, multiple plants and agriculture byproducts have shown promising results in textile dyeing with increasing sustainability and environmental friendliness. There is no doubt in the general acceptance of natural colorants to be utilized as promising substitutes to synthetic dyes for certain categories of textile products, minimizing the negative impact on the health and the…

Advancement in renewables is one of the most effective techniques for sustained long-term development, and nations across the globe are making efforts to change their economic and industrial structures in a bid to boost green growth. With the advent of the Fourth Industrial Revolution (4IR), the availability, access, and use of green technologies including renewable energy have significantly improved. Researches on the factors that influence renewable energy production are available. However, we are unaware of any previous research that examines the role of renewable energy innovation in the promotion of renewable energy production. As a result, this study evaluates the impact of technical innovation on green growth from 1993 to 2018, while accounting for real GDP, producer price index, and CO 2 emissions. Due to their pivotal status among the developing countries, our study has focused on the BRICS countries. By using a new panel quantile regression augmented with the method of moments, the empirical findings suggest that the influence of renewable energy innovation on renewable…

The next generation of wireless communication networks will rely heavily on machine learning and deep learning. In comparison to traditional ground-based systems, the development of various communication-based applications is projected to increase coverage and spectrum efficiency. Machine learning and deep learning can be used to optimize solutions in a variety of applications, including antennas. The latter have grown popular for obtaining effective solutions due to high computational processing, clean data, and large data storage capability. In this research, machine learning and deep learning for various antenna design applications have been discussed in detail. The general concept of machine learning and deep learning is introduced. However, the main focus is on various antenna applications, such as millimeter wave, body-centric, terahertz, satellite, unmanned aerial vehicle, global positioning system, and textiles. The feasibility of antenna applications with respect to conventional methods, acceleration of the antenna design process, reduced number of simulations, and better…

Climate change has the greatest negative impact on low-income countries, which burdens agricultural systems. Climate change and extreme weather events have caused Ethiopia's agricultural production to decline and exacerbated food insecurity over the last few decades. This study investigates whether farmers' awareness and perceptions of climate change play a role in climate change adaptation using climate-smart agricultural practices. To collect data, 385 households in Southern Ethiopia were sampled using a multistage sampling. A Heckman probit two-stage selection model was applied to investigate the factors influencing farmers' perceptions to climate change and adaptation measures through adoption of climate-smart agriculture practices, complemented with key informant interviews and focused group discussions. The results indicated that most farmers (81.80%) perceived that the local climate is changing, with 71.9% reporting increased temperature and 53.15% reporting decreasing rainfall distribution. Therefore, farmers attempted to apply some adaptation practices, including soil and…

Deep eutectic solvents (DES) are promising reaction media where interesting catalytic processes can be carried out. In theory, most of these mixtures are environmentally friendly, being an alternative to traditionally pollutant organic solvents used in several processes related to organic chemistry and biotechnology. However, recent studies show contradictory results regarding their toxicity. The method selected to perform toxicity studies could be significantly conditioned by some of the physical properties displayed by the DESs. Also, the metabolic capabilities of the organisms/cells used to monitor their toxicity are influenced by their physical properties. In this review, relevant physical-chemical properties for toxicity studies are summarized. The advantages/disadvantages of the used tests to monitor their toxicity and biodegradability in connection with the chosen organisms/cells are discussed, shedding light on their limitations. These findings could be taken as a starting point for designing more accurate DESs toxicity studies covering a wider spectrum of organisms and…

In the current study, a direct S-scheme titanium dioxide/graphitic carbon nitride (TiO 2 /g-C 3 N 4 ) heterojunction structure was fabricated via simultaneous calcination of TiO 2 precursors and g-C 3 N 4 . Guava leaf extract was utilized as a reductant for TiO 2 production through a green synthetic method, and g-C 3 N 4 was prepared by thermal decomposition of melamine. The pristine and nanocomposite photocatalysts were characterized by XRD, FTIR, BET, TGA, HRTEM, UV–vis DRS, and PL to elucidate their physicochemical properties. The photocatalytic activity of synthesized photocatalysts was examined through the degradation of rhodamine B (RhB) and methylene blue (MB) dyes under simulated solar light irradiation. The nanocomposite exhibited commendable photocatalytic performances with 96% degradation efficiency of RhB attained in 120 min and 95% degradation efficiency of MB achieved in 150 min. The enhanced photocatalytic activities were attributable to visible light-harvesting characteristics and the formation of an S-scheme heterojunction system between two catalysts which promotes…

Since Mark Zuckerberg's announcement about the development of new three-dimensional virtual worlds for social communication, a great debate has been raised about the promise of such a technology. The metaverse, a term formed by combining meta and universe, could open a new era in mental health, mainly in psychological disorders, where the creation of a full-body illusion via digital avatar could promote healthcare and personal well-being. Patients affected by body dysmorphism symptoms (i.e., eating disorders), social deficits (i.e. autism) could greatly benefit from this kind of technology. However, it is not clear which advantage the metaverse would have in treating psychological disorders with respect to the well-known and effective virtual reality (VR) exposure therapy. Indeed, in the last twenty years, a plethora of studies have demonstrated the effectiveness of VR technology in reducing symptoms of pain, anxiety, stress, as well as, in improving cognitive and social skills. We hypothesize that the metaverse will offer more opportunities, such as a more complex, virtual realm…

Objective: Clinical reasoning as an essential skill for psychiatrists, especially in forensic psychiatry, relies on their thinking and decision-making skills. However, not all psychiatrists are aware of their decision-making styles. This study examines the validity and reliability of the Indonesian translation of the Decision Style Scale (DSS) instrument among general psychiatrists in the Indonesian forensic psychiatry setting. Method: This is a cross-sectional study involving 32 general psychiatrists from all nine psychiatric residency training centers in Indonesia. The study was conducted between August 2020 and February 2021. The translation process involved certified independent translators. The validity was tested using Item-Level Content Validity Index (I-CVI), Scale-Level Level Content Validity Index (S-CVI), and item-total correlation. Internal consistency reliability was measured using Cronbach's alpha. Results: After translation, the instrument was sent back and received feedback from the original authors of DSS. The final version of DSS was valid with an I-CVI score of…

Background Poor medication adherence among patients with Chronic Diseases is one of the significant health problems globally. Despite this, evidence on chronic medication adherence in low and middle-income countries is unclear. Objective This scoping review aimed to identify factors influencing poor medication adherence amongst patients with chronic diseases in low and middle-income countries. Methods We searched studies exploring factors influencing poor medication adherence amongst patients in low and middle-income countries across the following databases published between 2008 to 2018: Public or publisher Medline, Google scholar, Cumulated Index to Nursing and Allied Health Literature, Health Source, and Medline with full text via Elton B. Stephen's Company host. Methodological quality assessment of the primary studies was done as recommended by Levac , Colquhoun, and O'Brien (2010) review using a Mixed-Method Appraisal Tool 2018. We reported the results following the Preferred Reporting Item for Systematic reviews and Meta-Analyses extension for Scoping Review guidelines.…

From environmental and sustainable development perspective, circular economy model is rarely applied in developing countries compared to developed nations. The aim of this paper is to review the overall scenario of the circular economy (CE) model in Bangladesh toward sustainable development. The study relies on the descriptive analysis of both qualitative and quantitative data, collected mostly from secondary sources with some in-depth interviews of the experts in the relevant field. The overall environmental status of Bangladesh, prospects, practices, and challenges of the circular economy model were thoroughly discussed in this paper. Though there are prospects to switching towards CE, the study reveals that the CE model's applicability is very limited in Bangladesh, being exercised mostly through recycling processes in some industries. Most importantly, we attempted to explore what is holding the CE practice in Bangladesh back, and iterated some policy, technical, and public participation barriers existing in Bangladesh. This paper will benefit the policymakers in developing…

Liposomes have been used extensively as micro- and nanocarriers for hydrophobic or hydrophilic molecules. However, conventional liposomes are biodegradable and quickly eliminated, making it difficult to be used for delivery in specific routes, such as the oral and systemic routes. One way to overcome this problem is through complexation with polymers, which is referred to as a liposome complex. The use of polymers can increase the stability of liposome with regard to pH, chemicals, enzymes, and the immune system. In some cases, specific polymers can condition the properties of liposomes to be explicitly used in drug delivery, such as targeted delivery and controlled release. These properties are influenced by the type of polymer, crosslinker, interaction, and bond in the complexation process. Therefore, it is crucial to study and review these parameters for the development of more optimal forms and properties of the liposome complex. This article discusses the use of natural and synthetic polymers, ways of interaction between polymers and liposomes (on the surface, incorporation in…

This paper provides a mini review of liquid biofertilizers, which have been proven to perform better than the other forms in lasting for longer periods of time, improving crop quality, and requiring less amounts for application. The production of liquid biofertilizers, types of liquid inoculants, and their effect on plant growth are covered in this review. Liquid biofertilizers can be made from wastes and by-products of several industries, making zero or near-zero discharge possible and thus gearing towards circular economy. Despite their usefulness in enhancing crop quality and eco-friendliness, in order to compete with chemical fertilizers, there are a number of challenges to overcome, such as extending the shelf life, making them more susceptible to seasonal climate conditions and soil types, and development of suitable machineries for production and application. More field trials, cost-benefit analysis and long-term studies should also be evaluated for commercialization purposes.

Acquired resistance during cancer treatment is unfortunately a frequent event. There are several reasons for this, including the ability of the ATP-binding cassette transporters (ABC transporters), which are integral membrane proteins, to export chemotherapeutic molecules from the interior of the tumor cells. One important member of this family is the protein known as Permeability Glycoprotein (P-Glycoprotein, P-gp or ABCB1). Its clinical relevance relies mainly on the fact that the inhibition of P-gp and other ABC transporters could result in the reversal of the multidrug resistance (MDR) phenotype in some patients. Recently, other roles apart from being a key player in MDR, have emerged for P-gp. Therefore, this review discusses the relationship between P-gp and MDR, in addition to the possible role of this protein as a biomarker in cancer.

Bruchids are most pernicious pest of stored grain pulses, especially in the tropical and subtropical areas. They penetrate into the fully grown matured pods, grains in fields and also during post-harvest storage. Among bruchids, Callosobruchus maculatus is the prominent pest having ubiquitous distribution. Chemical/synthetic insecticides provides adequate control against the C. maculatus on the pulses. However, the use of synthetic insecticides induces adverse health outcomes in agricultural workers and many causes various diseases such as cancers, genomic damage, oxidative stress, neurological disorders and respiratory, metabolic and thyroid effects. Therefore, alternative effective, safe and sustainable pest control, integration of different compatible methods should be taken into considerations. One of the possible managements might be use of traditional as well modern pest management practices. Traditional techniques include sealed containers, inert materials, harvesting time, alternate host, intercropping, storing un-threshed pulses, cleanliness, vegetable oil etc. Modern…

Assessment Tools have become the de facto method to address sustainability issues within the built environment. They provide a measurable third-party approach to ensuring sustainability design and directives are met through the use of indictors, criteria's and credit system. A key challenge is that the existing tools such as BREEAM Communities and LEED Neighbourhood Development address a wider community but cannot efficiently address the more nuanced and context specific sustainability requirements of campuses. However, the approach of utilizing credits, indicator and criteria systems is a tactic that campus planners have slowly began to imbibe. This is even more critical to sustainable development cities due to the huge amounts of land and human resources consumed on campuses; However, gaps exist within the currently existing Campus Sustainability Assessment Tools (CSAT) that have been developed. Generally. Though studies have identified trends and gaps in neighbourhood and building assessment tools, no comprehensive study has investigated the potential gaps from the newly emerging…

The development of acaricide resistance in ticks infesting cattle is a major problem in the livestock industry in tropical and subtropical regions worldwide. To determine the current global trends and prevalence of acaricide resistance development (ARD) in tick populations of cattle, a systematic review and meta-analysis with an emphasis on Rhipicephalus (Boophilus) microplus was conducted. Data searches from five English electronic databases yielded 88 journal articles published between 1992 and 2020. In total, 218 in - vitro bioassays were used to investigate 3939 tick populations of cattle; of these, the 57.6% that exhibited ARD were largely limited to South America (Brazil), Central America (Mexico), and Asia (India). A total of 3391 of these tick populations were R. (B.) microplus , of which 2013 exhibited ARD. Random effects meta-analyses indicated that the exhibition of ARD was higher in R. (B.) microplus (66.2%) than in other tick species. Global prevalence estimates of ARD in R. (B.) microplus vary as a function of geography, detection methods, and acaricide compounds. In…

Nowadays, engineers are toiling away to achieve the maximum possible wind energy harvesting with low costs through enhancing the performances of WECSs in efforts to realize the wind power future forecasts. In fact, achieving this is basically not an easy task due to the intricacies that partly stem from the stochastic nature of wind energy. Further, the efforts in this regard can also be impacted by the ongoing trends in various wind energy conversion-related technologies, and engineering approaches. Hence, the wind power optimization is determined depending on the types of WECS technologies, output power smoothing, and design development approaches that be employed. Currently, the variable speed operations-based WECS technologies are generally opted in wind farm applications. Meanwhile, power management system is the heart of a WECS, where smoothing output power with reducing costs could be implemented. On the other hand, the automated control strategies were reported in literatures to better optimize WECSs' performances particularly in terms of costs compared to ESS devices. On…

Refined sugar is a processed product containing 99% sucrose, which is obtained from sugarcane (70%) or sugar beet (30%). In modern societies, sugar continues to play a significant role in the diet, recognised not only for its flavour and special sweetening properties but also for its role in food preservation. On the other hand, a high consumption of refined sugar is associated with non-communicable diseases and many health issues such as a high risk of dental caries, overweight and neurodevelopmental disorders in children. Alternatives like unrefined sugars have generated a lot of interest as a healthy substitute due to their nutraceutical properties. This paper is aimed to review the beneficial effects of sugar derived from natural sources and highlight health problems that could be caused by refined processed sugar. Refined sugar is frequently used in variety of items including processed foods, soft drinks or ice creams although it is considered unhealthy due to its high salt and sugar content as well as added fats and artificial coloring. Natural sugars are preferred because…

Drawing on the resource-based view, new public management theory, and innovation systems theory, this study examines the relationships between internal control systems (ICSs) and organizational performance in Vietnamese public sector organizations (PSOs), with particular emphasis on the mediating role of intensity of innovation and the moderating role of transformational leadership. Data from 319 PSOs in Vietnam corroborated our hypothesis that ICSs boost the intensity of innovation, which has a beneficial effect on organizational performance. Additionally, data demonstrated that intensity of innovation fully mediated the relationships between ICSs and organizational performance, and that transformational leadership reinforced the mediating relationships. The findings have implications for our understanding of the function of leadership and ICSs in managing innovation and promoting performance in PSOs in emerging markets.

The green and facile synthesis of metallic silver nanoparticles (AgNPs) is getting tremendous attention for exploring superior applications because of their small dimensions and shape. AgNPs are already proven materials for superior coloration, biocidal, thermal, UV-protection, and mechanical performance. Originally, some conventional chemical-based reducing agents were used to synthesize AgNPs, but these posed potential risks, especially for enhanced toxicity. This became a driving force to innovate plant-based sustainable and green metallic nanoparticles (NPs). Moreover, the synthesized NPs using plant-based derivatives could be tuned and regulated to achieve the required shape and size of the AgNPs. AgNPs synthesized from naturally derived materials are safe, economical, eco-friendly, facile, and convenient, which is also motivating researchers to find greener routes and viable options, utilizing various parts of plants like flowers, stems, heartwood, leaves and carbohydrates like chitosan to meet the demands. This article intends to provide a comprehensive review of all aspects…

Water quality index (WQI) can express overall water quality status in a single term. As such, the application of daily WQI assessment should help the general public be more aware of the condition of the surface water around them. As the longest and biggest river in the West Java Province, the Citarum River plays an important role in the life of the community and ecosystem around it. Therefore, this research evaluated which WQI assessment method was best suited for determining the Citarum River's water quality. We utilized West Java Province monitoring data collected from four monitoring stations along the Upstream Citarum. The WQI was calculated using the National Sanitation Foundation WQI (NSF WQI), Canadian Council of Ministers of the Environment WQI (CCME WQI), and Oregon Water Quality Index (OWQI) assessment methods. Nine years of monitoring data were grouped and analyzed according to wet vs. dry months, wet vs. dry years, monitoring station, and year. Using the NSF WQI assessment method, the Citarum River obtained a 'Fair' and 'Bad' water quality grade with WQI ranging between…

Non-performing loans (NPLs, henceforth) represent the main challenge that jeopardizes the steadiness of the banking sector. The purpose of this study is to explore the main determinants of banks' non-performing loans in emerging markets. To better understand the hidden aspects of these determinants, the current research employs a panel approach and dynamic data estimates through Generalized Methods of Moments (GMM) using data of 53 banks listed in five Middle East and North African (MENA) emerging markets between 2000 and 2019. This study documents that GDP growth, unemployment, bank capitalization, bank performance, bank operating inefficiency, bank ownership concentration, inflation, sovereign debt and bank size are the main determinants of NPLs, whereas, loan growth, bank diversification and interbank competition were found to have an insignificant impact on NPLs. This analysis is motivated by the recent economic changes surrounding the financial systems in emerging countries with the aim to provide new evidence and insights. The results show that non-performing loans can be…

The commitment of higher education to produce job-ready and highly competitive graduates requires that it endow graduates with broad knowledge and innovative technologies, including business skills facing various challenges of project-based digital learning for future achievement. The study aimed to analyze the effect of Project-Based Online Learning (PBOL) and student engagement on academic achievement. The research method used a mixed-method convergent parallel design. Qualitative data collection is through interviews, observational and documentation forms, and quantitative data is through questionnaires and portfolios. A qualitative data interpretation used content analysis, while quantitative data used the Two-Way ANOVA test. The results showed that students' perceptions of implementing the PBOL method and student engagement increased their academic performance to become new entrepreneurs through the experience they gained during project-based learning. This method could also create a fun learning atmosphere that affects student engagement behavior. The research contributes an…

Neurodegenerative diseases, featured by progressive loss of structure or function of neurons, are considered incurable at present. Movement disorders like tremor and postural instability, cognitive or behavioral disorders such as memory impairment are the most common symptoms of them and the growing patient population of neurodegenerative diseases poses a serious threat to public health and a burden on economic development. Hence, it is vital to prevent the occurrence of the diseases and delay their progress. Vitamin D can be transformed into a hormone in vivo with both genomic and non-genomic actions, exerting diverse physiological effects. Cumulative evidence indicates that vitamin D can ameliorate neurodegeneration by regulating pertinent molecules and signaling pathways including maintaining Ca 2+ homeostasis, reducing oxidative stress, inhibiting inflammation, suppressing the formation and aggregation of the pathogenic protein, etc . This review updates discoveries of molecular mechanisms underlying biological functions of vitamin D in neurodegenerative diseases including…

This study investigated the cost competitiveness, using total cost of ownership (TCO) analysis, of hydrogen fuel cell electric vehicles (FCEVs) in heavy duty on and off-road fleet applications as a key enabler in the decarbonisation of the transport sector and compares results to battery electric vehicles (BEVs) and diesel internal combustion engine vehicles (ICEVs). Assessments were carried out for a present day (2021) scenario, and a sensitivity analysis assesses the impact of changing input parameters on FCEV TCO. This identified conditions under which FCEVs become competitive. A future outlook is also carried out examining the impact of time-sensitive parameters on TCO, when net zero targets are to be reached in the UK and EU. Several FCEVs are cost competitive with ICEVs in 2021, but not BEVs, under base case conditions. However, FCEVs do have potential to become competitive with BEVs under specific conditions favouring hydrogen, including the application of purchase grants and a reduced hydrogen price. By 2050, a number of FCEVs running on several hydrogen scenarios show a TCO…

In order to sustain business operations during the COVID-19 pandemic, nearly all industries have to adopt online technology and social media marketing activities (SMMAs). Globally, portable tech gadgets are rapidly expanding, but empirical studies on SMMAs in relation to portable tech gadgets in Malaysia have remained scarce. Therefore, this study examined the elements of SMMAs and their influence on brand equity in terms of brand awareness (BBA) and brand image (BBI) as well as brand loyalty (BRL) and willingness to pay premium price (WPP) among Malaysian consumers of portable tech gadgets users. Five components of SMMAs, namely entertainment (ENT), interactivity (INT), trendiness (TRE), customisation (CUS), and electronic word-of-mouth (EWOM), were examined to understand how SMMAs influence BBA, BBI, BRL, and WPP. An online survey was conducted with 1332 Malaysian youths who used social media platforms maintained by portable tech gadget brands as their marketing strategies. The gathered data were evaluated using structural equation modelling. The study's results indicated the…

Global competitiveness thrives on meeting energy demand, and the need to counter the effects of environmental threads dispatched by the combustion of fossil fuels became the driving forces that upended the renewed commitment and growing interest in renewables. Alternatively, green energy provides a twofold solution to energy and environmental crisis in a sustainable, economically viable, and eco-friendly manner. However, energy from biomass, especially biodiesel is considered an attractive substitute for mineral diesel, with the proficiency of meeting future energy demand. Inevitably, biodiesel exhibits poor cold flow properties leading to plugging and gumming of filters, whereas oxidation stability results in sediments and gum formation. These effects present a legitimate concern to producers and the automotive sector. Many reviews on the use of antioxidants to improve biodiesel's cold flow and oxidative stability flooded the literature independently. Yet, a review encompassing the factors inducing biodiesel's poor cold flow, oxidation stability, their effects on engine…

The quest for waste reduction, quality improvement and operational efficiency during the assembly process of the railcar bogie necessitates this study. Using a case study approach, this study employs the Lean Six Sigma (LSS) approach for process improvement of the railcar bogie assembly process. Primary data relating to the assembly process such as the labour and material flow, up and down times were collected at every stage of the assembly operation. The improvement process of the assembly process featured the use of some Lean tools such as the Kaizen, Value Stream Mapping, Pareto chart, Single-Minute Exchange of Die (SMED) and 5S. The investigation of the current assembly process with the use of the LSS technique indicates that the process efficiency is low due to waste generation. The results obtained showed significant improvement in the process cycle efficiency (PCE) by 46.8%, via the implementation of the Kaizen continuous process improvement approach, 27.9% reduction in the lead-time, 59.3% increase in the value added time and 71.9% reduction in the non-value added time after…

Isopropyl 1-benzoyl-4-(benzoyloxy)-2,6-diphenyl-1,2,5,6-tetrahydropyridine-3-carboxylate (IDPC) was synthesized and characterized via spectroscopic (FT-IR and NMR) techniques. Hirshfeld surface and topological analyses were conducted to study structural and molecular properties. The energy gap (E g ), frontier orbital energies (E HOMO , E LUMO ) and reactivity parameters (like chemical hardness and global hardness) were calculated using density functional theory with B3LYP/6–311++G (d,p) level of theory. Molecular docking of IDPC at the active sites of SARS-COVID receptors was investigated. IDPC molecule crystallized in the centrosymmetric triclinic ( P 1 ¯ ) space group. The topological and Hirshfeld surface analysis revealed that covalent, non-covalent and intermolecular H-bonding interactions, and electron delocalization exist in the molecular framework. Higher binding score (-6.966 kcal/mol) of IDPC at the active site of SARS-COVID main protease compared to other proteases suggests that IDPC has the potential of blocking polyprotein maturation. H-bonding and π-cationic and…

This study aims to explore the multicultural education paradigm embedded in the fundamental constitutions, laws, and social rules in the Indonesian contexts. Achieving this aim, this research applied a meta-analysis approach by extracting multicultural themes from essential documents that are available publicly. The keywords for meta-analysis of the documents are culture, multiculturalism, and education. The findings of the study identified that the multicultural education paradigms, such as unity in diversity, equality, cultural identity, and social justice, are the essential vital themes appear in this research. Since there is a scarce study on exploring the essence of multicultural education within the origin of the Indonesian communities, this study contributes to the promotion and debates of multicultural education nationally and internationally. This study recommends a further in-depth investigation of how educators, students, policy-makers, and communities perceive and implement multicultural values within their communities to achieve peaceful and harmonious lives.

The usage of recycled fibers has achieved enormous importance in the textile sector due to growing environmental awareness, legal requirements for more sustainability and the cost of raw materials. Recycled cotton fibers derived from mechanical shredding of textile waste possess lower quality values and therefore they are spun through blending with other fibers in rotor spinning system for the production of coarse yarns (10-20 Ne) to make denim, towel and home furnishing. Owing to low fiber migration, rotor yarns require high twist during spinning which makes them stiffer and poorly moisture absorbent. Rotor yarns also feel harsh in skin contact due to the presence of wrapper fibers in the yarn surface. Intending to make knit top garments like T-shirts and polo shirts, apparel manufacturers nowadays demand recycled fiber-contained soft and high moisture absorbent yarn that can be produced in ring spinning system. In the current endeavor, cotton fibers reclaimed from pre- and post-consumer textile waste were blended with virgin cotton and soft-twisted 30 Ne yarns were manufactured in…

This research article concerns a study of economic growth influences on carbon dioxide emissions in 20 selected Sub Saharan African (SSA) countries. The study also intends to reexamine energy consumption, tourism sector and population effect on carbon dioxide emissions. The empirical research applies panel linear regression model for the data obtained in these 20 SSA countries throughout 2000 to 2020. The empirical estimation techniques employed in the analysis consist of pooled ordinary least square (OLS), fixed effects model (FEM), random effects model (REM) and robust fixed model, including diagnostic tests such as endogeneity, heteroscedasticity and other measurements. The empirical analysis using the robust fixed effects model has established significant associations between economic growth, energy consumption, tourism sector and population on carbon dioxide emissions in SSA countries between 2000 and 2020. This study has established that a 1% increase in economy growth increases the carbon dioxide emission level by approximately 0.02%. A study has identified that SSA…

BACKGROUND: This study aimed to validate the Persian version of Maslach Burnout Inventory for Medical Personnel (MBI-HSS-MP), an instrument developed to capture burnout for health professionals. The specific aims were to psychometrically assess the Persian MBI-HSS-MP in relation to its structure, test-retest reliability, and item properties. METHODS: The study setting was all eight hospitals in Qazvin province, Iran (study period from 10 September to 16 November 2020). Health professionals of physicians (n = 106) and nurses (n = 200) participated in the study. The psychometric properties of the 22-item MBI-HSS-MP was then examined for its factor structure via confirmatory factor analysis (CFA) and Rasch models, test-retest reliability, item fit, and differential item functioning (DIF). RESULTS: The MBI-HSS-MP was verified as having a three-factor structure and each item was embedded well in its belonging construct (comparative fit index = 0.941, Tucker-Lewis index = 0.929 derived from CFA results; infit and outfit MnSq = 0.71 to 1.38 derived from Rasch models). Test-retest…