About this source
The University of New Mexico’s open drug compendium. Approvals by FDA, EMA and PMDA with dates, indications, off-label uses and contraindications, FDA and MeSH pharmacologic classes, defined daily dose, mechanism-of-action targets with activities, and disproportionality signals from FDA adverse-event reports. CC BY-SA 4.0; snapshot 2023-11.
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“Find randomised trials of an intervention for a condition and list their identifiers.”
What comes back: Studies with registry or PubMed identifiers and key design details.
What the assistant can do with it
The 4 tools this server offers to Kahubi. The assistant picks the right one for each question.
drugcentral_searchFind DrugCentral drugs by name, brand or code name.
drugcentral_get_drugDrugCentral profile: approvals by agency with date and company, indications, off-label uses and contraindications, pharmacologic classes (FDA EPC and MoA, MeSH, ChEBI), defined...
drugcentral_targetsBioactivity targets of a drug from DrugCentral: target name, gene, UniProt, class, action type, activity (pActivity = -log10 molar, so 9 = 1 nM) with type and source; mechanism-...
drugcentral_adverse_eventsFAERS adverse-event disproportionality signals for a drug from DrugCentral: MedDRA preferred term, number of reports with the event, and log-likelihood ratio (LLR) against the s...
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- ClinicalTrials.govSearch registered clinical trials, read full study records, posted results and eligibility criteria.
- Clinical evidence (trials, FDA labels, adverse events)ClinicalTrials.gov, openFDA drug labels, adverse-event reports and approvals alongside PubMed.
- CDC data and WONDERUS public-health datasets (data.cdc.gov) and CDC WONDER mortality and natality queries.
- NCATS Inxight DrugsEvery FDA-registered substance with its UNII, plus NCATS-curated approval status, indications, targets and pharmacokinetics.
- openFDAFDA drug and device adverse events, recalls, labels and shortages.