About DrugCentral
The University of New Mexico’s open drug compendium. Approvals by FDA, EMA and PMDA with dates, indications, off-label uses and contraindications, FDA and MeSH pharmacologic classes, defined daily dose, mechanism-of-action targets with activities, and disproportionality signals from FDA adverse-event reports. CC BY-SA 4.0; snapshot 2023-11.
Questions you can ask DrugCentral
Type them into Kahubi’s chat once DrugCentral is connected.
“What are the known mechanism-of-action targets of imatinib and their potencies?”
What comes back: Targets with gene, UniProt id, action type and activity values (pActivity) with sources.
“Which off-label uses and adverse-event signals does DrugCentral list for quetiapine?”
What comes back: Off-label indications plus FAERS disproportionality signals with report counts and likelihood ratios.
DrugCentral MCP tools
The 4 tools the DrugCentral server offers to Kahubi. The assistant picks the right one for each question.
drugcentral_searchFind DrugCentral drugs by name, brand or code name.
drugcentral_get_drugDrugCentral profile: approvals by agency with date and company, indications, off-label uses and contraindications, pharmacologic classes (FDA EPC and MoA, MeSH, ChEBI), defined...
drugcentral_targetsBioactivity targets of a drug from DrugCentral: target name, gene, UniProt, class, action type, activity (pActivity = -log10 molar, so 9 = 1 nM) with type and source; mechanism-...
drugcentral_adverse_eventsFAERS adverse-event disproportionality signals for a drug from DrugCentral: MedDRA preferred term, number of reports with the event, and log-likelihood ratio (LLR) against the s...
Using DrugCentral in Kahubi
- Hosted by Kahubi. Kahubi runs this server itself so it stays reliable enough for research use.
- Cited, checkable answers. Results are treated as retrieved material and cited with the source’s own identifiers, so you can open every record the answer relied on.
- Your files stay private. Only the search the assistant writes for your question is sent to DrugCentral.
More medical & clinical sources
- PubMed & Europe PMCBiomedical literature: search, MeSH terms, related articles, citations and lawful full text.
- ClinicalTrials.govSearch registered clinical trials, read full study records, posted results and eligibility criteria.
- Clinical evidence (trials, FDA labels, adverse events)ClinicalTrials.gov, openFDA drug labels, adverse-event reports and approvals alongside PubMed.
- CDC data and WONDERUS public-health datasets (data.cdc.gov) and CDC WONDER mortality and natality queries.
- NCATS Inxight DrugsEvery FDA-registered substance with its UNII, plus NCATS-curated approval status, indications, targets and pharmacokinetics.
- openFDAFDA drug and device adverse events, recalls, labels and shortages.