About NCATS Inxight Drugs
The NIH NCATS drug portal built on the FDA Global Substance Registration System. Look up a drug, salt, biologic or excipient by name, code, UNII or CAS and get its names, cross-references (CAS, PubChem, ChEMBL, RxCUI, ATC, EMA, orphan designations), US development status and first approval, originator, indications with highest phase, primary targets with potency, and curated human pharmacokinetics and CYP/transporter interactions. Public domain.
Questions you can ask NCATS Inxight Drugs
Type them into Kahubi’s chat once NCATS Inxight Drugs is connected.
“What are the half-life and main CYP interactions of apixaban?”
What comes back: Curated human pharmacokinetics with dose and population, plus CYP and transporter interactions with sources.
“Give me the UNII, CAS number, ATC code and first US approval date for metformin.”
What comes back: The substance record with identifiers, development status, approval year and cross-references.
NCATS Inxight Drugs MCP tools
The 3 tools the NCATS Inxight Drugs server offers to Kahubi. The assistant picks the right one for each question.
inxight_search_substancesSearch NCATS Inxight Drugs (FDA GSRS substances plus NCATS-curated drug data, 167k substances) by name, brand, code, UNII or CAS.
inxight_get_substanceOne substance by UNII, name, CAS or uuid: names (INN, brand, codes), cross-references (CAS, PubChem, ChEMBL, RxCUI, ATC, MeSH, EMA, orphan designations …), structure, NCATS-cura...
inxight_pharmacologyNCATS-curated pharmacology for one substance: human pharmacokinetics (Cmax, AUC, half-life, fraction unbound, with dose, route, population and source), drug-drug interaction rol...
Using NCATS Inxight Drugs in Kahubi
- Hosted by Kahubi. Kahubi runs this server itself so it stays reliable enough for research use.
- Cited, checkable answers. Results are treated as retrieved material and cited with the source’s own identifiers, so you can open every record the answer relied on.
- Your files stay private. Only the search the assistant writes for your question is sent to NCATS Inxight Drugs.
More medical & clinical sources
- PubMed & Europe PMCBiomedical literature: search, MeSH terms, related articles, citations and lawful full text.
- ClinicalTrials.govSearch registered clinical trials, read full study records, posted results and eligibility criteria.
- Clinical evidence (trials, FDA labels, adverse events)ClinicalTrials.gov, openFDA drug labels, adverse-event reports and approvals alongside PubMed.
- CDC data and WONDERUS public-health datasets (data.cdc.gov) and CDC WONDER mortality and natality queries.
- openFDAFDA drug and device adverse events, recalls, labels and shortages.
- EMA medicines (EU authorisations)Centrally authorised EU medicines, orphan designations, safety communications and shortages from the European Medicines Agency.